Phenoxpen

Phenoxpen

COMPOSITIONS :

Each film coated tablet contains :

• Phenoxymethylpenicillin potassium……………………………………… 1,000,000 IU
• Excipients : q.s ………………………………………………………………………..one tablet

THERAPEUTIC PROPERTIES

It is an antibiotic from the beta-lactam family, in the group of natural penicillin , specifically phenoxymethylpenicillins.

INDICATIONS

Indications are limited to infections caused by organisms defined as sensitive (see Pharmacodynamics):

• Curative use:
  – Documented sore throat caused by group A beta-hemolytic streptococcus.
  – Mild skin infections caused by sensitive organisms.
• Prophylaxis:
  – Prevention of relapses of Acute Rheumatic Fever (ARF).
  – Prevention of recurring erysipelas.
  – For contact persons in the vicinity of a case of scarlet fever.
  – Pneumococcal infections in splenectomized patients, major sickle cell patients, and other functionally asplenic individuals

CONTRAINDICATIONS

• Allergy to beta-lactams (penicillins and cephalosporins).
• Methotrexate (see Interactions).

IN CASE OF DOUBT, IT IS ESSENTIAL TO CONSULT YOUR DOCTOR OR PHARMACIST.

WARNING AND PRECAUTION :

·       The occurrence of any allergic manifestation requires discontinuation of the treatment and initiation of appropriate treatment.

SIDE EFFECTS

• Allergic reactions: Fever, hives, angioedema, and, rarely, anaphylactic shock.
• Gastrointestinal disorders: Nausea, vomiting, diarrhea, and black tongue in case of prolonged treatment.
• Hematological reactions (reversible): Anemia, thrombocytopenia, leukopenia, coagulation disorders.

DOSAGE

• Curative treatment:
  The daily dosage should be divided into 2 to 3 doses for sore throats, or 3 to 4 doses for other indications.
  • Adult: 2,000,000 to 4,000,000 IU/day.
  • Infants and children up to 40 kg: 50,000 to 100,000 IU/kg/day.
  Treatment duration: For sore throats, treatment should last for 10 days.
• Prophylaxis:
  The daily dosage should be divided into two doses.
  • Infants and children:
  • Up to 10 kg: 100,000 IU/kg/day.
  • From 10 kg to 40 kg: 50,000 IU/kg/day, without exceeding 2,000,000 IU/day.
  • Adults: 2,000,000 IU/day; prophylaxis should continue for at least 2 years after splenectomy

CONSERVATION

• Store at a temperature below 30°C, away from light and humidity.
• Keep out of reach and sight of children.
• Do not use after the expiration date on the package.