Griseofulvine

GRISEOFULVINE

COMPOSITIONS

Each tablet contains :

Griseofulvin : …………………………………………………………………………….500 mg

Excipients : q.s. ………………………………………………………………………One tablet

THERAPEUTIC PROPERTIES

Antifungal/ Antifungal antibiotic

INDICATIONS

• Cutaneous dermatophyte infections: ringworm, Habra’s marginal eczema, and mycotic intertrigo.
• Nail dermatophyte infections.
• Hair dermatophyte infections: scalp ringworm

CONTRAINDICATIONS

• Allergy to griseofulvin.
• Systemic lupus erythematosus and related syndromes.

IN CASE OF DOUBT, IT IS ESSENTIAL TO SEEK

THE ADVICE OF YOUR DOCTOR OR PHAMACIST

WARNING AND PRECAUTION

• Monitor the blood count during long-term treatment (lasting more than one month) and at high doses (> 1.5 g per day).
• Increase monitoring in cases of liver insufficiency.
• Avoid sun exposure during and immediately after treatment.
• Drug interactions: Alcohol and medications containing it; estrogen-progestogen contraceptives (oral contraceptives).

SIDE EFFECTS

• Neurological manifestations: Primarily headaches, less commonly dizziness, insomnia, and drowsiness.
• Gastrointestinal disorders: Anorexia, nausea, changes in taste, and a sensation of thirst.
• Allergic skin reactions and photosensitivity.

DOSAGE AND ADMINISTRATION

Adults: The usual dosage is 500 mg to 1 g per day, taken in 2 doses during meals.

Children: 10 mg to 20 mg/kg per day.

The tablets should be swallowed with a large glass of water.

The duration of treatment depends on the location:

• For the skin: 4 to 8 weeks.
• For the scalp and ringworm: 6 to 8 weeks.
• For nail mycoses: 4 to 12 weeks.

STORAGE

• Store at a temperature below 30°C, protected from light and moisture.
• Keep out of reach of children.
• Do not use after the expiration date shown on the box