SQUABB-6V4

SQUABB-6V4

COMPOSITIONS :
Each tablet contains :

• Phenoxymethylpenicillin…………………………………….. 400,000 IU
• Excipients : q.s. ……………………………………………………..one tablet

THERAPEUTIC PROPERTIES
This is an antibiotic from the beta-lactam family, specifically from the natural penicillins group, of the phenoxymethylpenicillin type.
INDICATIONS
Indication are limited to infections caused by bacteria known to be sensitive to this antibiotics.
Therapeutic use :

• Documented streptococcal tonsillitis caused by Group A beta-hemolytic streptococcus
• Mild skin infections caused by sensitive organisms

Prophylactic use :

• Prevention of recurrent rheumatic fever (RRF)
• Prevention of recurrent erysipelas
• In close contracts of individuals with scarlet fever
• Pneumococcal infection prevention in idividuals who are :
• Splenectomized
• Sickle cell patients
• Other functionally asplenic individuals

CONTREAINDICATIONS

• Allergy to beta-lactam antibiotics (Penicillins and cephalosporins)
• Concomitant use of methotrexate

IN CASE OF DOUBT, IT IS ESSENTIAL TO CONSULT YOUR DOCTOR OR PHARMACIST .

PRECEUTION

• The appearance of any allergic reaction required immediate discontinuation of the treatment and initiation of appropriate care.

SIDE EFFECT

–         Allergic reactions : fever, hives, angioedema (Quincke’s edema), and in rare cases, anaphylactic shock

–         Digestive issues : nausea, vomiting, diarrhea, black tongue with prolonged treatment

–         Reversible hematologic reactions : anemia, thrombocytopenia, leukopnia, and conagulation disorders.

DOSAGE AND ADMINISTRATION

Therapeutic Use :
Daily doses should be divided into 2-3 doses for tonsillitis, and 3-4 doses for other indications.

• Adults : 2,000,000 to 4,000,000 IU/day
• Infants and children up to 40 kg : 50,000 to 100,000 IU/kg/day
• Duration : 10 days for tonsillitis

Prophylactic Use :
Daily doses should be divided into two doses.

• Infants and children :
• Up to 10kg : 100,000 IU/kg/day
• From 10kg to 40kg : 50,000 IU/kg/day (not to exceed 2,000,000 IU/day)
• Adults : 2,000,000 IU/day
• Duration : Prophylaxis should continue for at least 2 years after splenectomy